Archive for July 12, 2011
Half life of IV fluid
NSS or RL 1 liter given- 200 cc intravascular expansion lasting for about 2 hours (cheap)
Albumin 5%- give 1 liter, expand by 500 cc. Lasts 24 hours. Expensive.
Albumin 25%- give 100cc, expand by 500 cc.
Hetastarch- give 1 liter, expand by 750 cc. Lasts 24-36 hours.
D40 – give 1 liter, expand by 800 cc. Lasts 24 hours.
D70 – give 1 liter, expand by 1000cc. Lasts 24 hours.
P0.1
About P0.1
The inspiratory depression of airways pressure, achieved after 100 ms of occlusion, is generally defined as the occlusion pressure or P0.1 and represents a valid indirect measurement of the activity of the respiratory centres. P0.1 is a reliable measurement of the intensity of the stimuli from the neurological centres to the peripheral respiratory muscles.
จาก studies ค่าP0.1ที่บ่งว่าผู้ป่วยสามารถ weaning สำเร็จ (+/-ไม่ต้องreintubate) อยู่ที่ 4.5-6cmH2O
จริงๆ จะเป็นค่า negative (represent pleural pressure) หาก drive น้อย occlusion pressure >-6 (เป็นลบน้อยกว่า)
หากมี drive occlusion pressure < -6 คืือดึง negative มากกว่าเดิม